E4F1
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Transcription factor E4F1 is a protein that in humans is encoded by the E4F1 gene.[1][2][3]
Function
The zinc finger protein encoded by this gene is one of several cellular transcription factors whose DNA-binding activities are regulated through the action of adenovirus E1A. A 50-kDa amino-terminal product is generated from the full-length protein through proteolytic cleavage. The protein is differentially regulated by E1A-induced phosphorylation. The full-length gene product represses transcription from the E4 promoter in the absence of E1A, while the 50-kDa form acts as a transcriptional activator in its presence.[3]
Interactions
E4F1 has been shown to interact with:
References
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Further reading
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External links
- E4F1 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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