TGFB1I1

Transforming growth factor beta-1-induced transcript 1 protein is a protein that in humans is encoded by the TGFB1I1 gene.

Interactions

TGFB1I1 has been shown to interact with:

• Androgen receptor,
• Dopamine transporter
• Hsp27,
• PTK2B,
• PTK2, and
• PTPN12.

Model organisms

Model organisms have been used in the study of TGFB1I1 function. A conditional knockout mouse line called Tgfb1i1^{tm1b(KOMP)Wtsi} was generated at the Wellcome Trust Sanger Institute. Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion. Additional screens performed: - In-depth immunological phenotyping

Tgfb1i1 knockout mouse phenotype

Characteristic	Phenotype
All data available at.
Peripheral blood leukocytes 6 Weeks	Normal
Haematology 6 Weeks	Normal
Insulin	Normal
Homozygous viability at P14	Normal
Homozygous Fertility	Normal
Body weight	Normal
Neurological assessment	Normal
Grip strength	Normal
Dysmorphology	Normal
Indirect calorimetry	Normal
Glucose tolerance test	Normal
Auditory brainstem response	Normal
DEXA	Normal
Radiography	Normal
Eye morphology	Normal
Clinical chemistry	Normal
Haematology 16 Weeks	Normal
Peripheral blood leukocytes 16 Weeks	Normal
Heart weight	Normal
Salmonella infection	Normal
Cytotoxic T Cell Function	Normal
Spleen Immunophenotyping	Normal
Mesenteric Lymph Node Immunophenotyping	Normal
Bone Marrow Immunophenotyping	Normal
Epidermal Immune Composition	Normal
Influenza Challenge	Normal

See also

• Transcription coregulator

External links

• TGFB1I1 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
• NURSA C148

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.