MCOLN2
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| Mucolipin 2 | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | MCOLN2 ; TRP-ML2; TRPML2 | ||||||||||||
| External IDs | OMIM: 607399 MGI: 1915529 HomoloGene: 12258 IUPHAR: 502 GeneCards: MCOLN2 Gene | ||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 255231 | 68279 | |||||||||||
| Ensembl | ENSG00000153898 | ENSMUSG00000011008 | |||||||||||
| UniProt | Q8IZK6 | Q8K595 | |||||||||||
| RefSeq (mRNA) | NM_153259 | NM_001005846 | |||||||||||
| RefSeq (protein) | NP_694991 | NP_001005846 | |||||||||||
| Location (UCSC) | Chr 1: 84.93 – 85 Mb |
Chr 3: 146.15 – 146.2 Mb |
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| PubMed search | [1] | [2] | |||||||||||
Mucolipin-2 also known as TRPML2 (transient receptor potential cation channel, mucolipin subfamily, member 2) is a protein that in humans is encoded by the MCOLN2 gene.[1] It is a member of the small family of the TRPML channels, a subgroup of the large protein family of TRP ion channels.
TRPML2 is associated with the Arf6-regulated trafficking pathway and is involved in the intracellular transport of membranes and membrane proteins.[2]
See also
- transient receptor potential cation channel, mucolipin subfamily, member 1 (MCOLN1)
- transient receptor potential cation channel, mucolipin subfamily, member 3 (MCOLN3)
References
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<references />, or <references group="..." />External links
- MCOLN2 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
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