RYR3

Ryanodine receptor 3
Ryanodine receptor 3
Available structures
PDB	Ortholog search: PDBe, RCSB
List of PDB id codes
	4ERV
Identifiers
Symbols	RYR3 ; RYR-3
External IDs	OMIM: 180903 MGI: 99684 HomoloGene: 68151 IUPHAR: 749 ChEMBL: 2062 GeneCards: RYR3 Gene
Gene ontology
Molecular function	• ryanodine-sensitive calcium-release channel activity; • calcium ion binding; • calmodulin binding; • calcium-release channel activity; • calcium-induced calcium release activity;
Cellular component	• cytosol; • integral component of membrane; • junctional membrane complex; • sarcoplasmic reticulum membrane; • perinuclear region of cytoplasm;
Biological process	• calcium ion transport; • striated muscle contraction; • ion transmembrane transport; • protein homotetramerization; • negative regulation of cytosolic calcium ion concentration; • transmembrane transport; • calcium ion transmembrane transport; • cellular response to calcium ion; • cellular response to magnesium ion; • cellular response to caffeine; • cellular response to ATP;
	Sources: Amigo / QuickGO
Orthologs
Species	Human
Entrez	6263
Ensembl	ENSG00000198838
UniProt	Q15413
RefSeq (mRNA)	NM_001036
RefSeq (protein)	NP_001027
Location (UCSC)	Chr 15:; 33.31 – 33.87 Mb
PubMed search	[1]
	v; t; e;

Ryanodine receptor 3 is a protein that in humans is encoded by the RYR3 gene.^[1] The protein encoded by this gene is both a calcium channel and a receptor for the plant alkaloid ryanodine. RYR3 and RYR1 control the resting calcium ion concentration in skeletal muscle.^[2]

References

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RYR3 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article on a gene on human chromosome 15 is a stub. You can help Wikipedia by expanding it.