Mestanolone

Mestanolone

Systematic (IUPAC) name
(5α,17β)-17-hydroxy-17-methylandrostan-3-one
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy category	US: X (Contraindicated)
Legal status	DEA Schedule III (US)
Routes of administration	Oral
Pharmacokinetic data
Bioavailability	99% oral
Protein binding	yes
Metabolism	Hepatic
Biological half-life	?
Excretion	Renal
Identifiers
CAS Number	521-11-9 N
ATC code	none
PubChem	CID: 10633
ChemSpider	10187 Y
UNII	S712YZ168E Y
KEGG	D01533 Y
ChEMBL	CHEMBL261514 Y
Synonyms	(5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-10,13,17-trimethyl-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-one
Chemical data
Formula	C20H32O2
Molecular mass	304.467 g/mol
SMILES O=C2C[C@@H]1CC[C@@H]3[C@@H]([C@@]1(C)CC2)CC[C@]4([C@H]3CC[C@@]4(O)C)C
InChI InChI=1S/C20H32O2/c1-18-9-6-14(21)12-13(18)4-5-15-16(18)7-10-19(2)17(15)8-11-20(19,3)22/h13,15-17,22H,4-12H2,1-3H3/t13-,15+,16-,17-,18-,19-,20-/m0/s1 Y Key:WYZDXEKUWRCKOB-YDSAWKJFSA-N Y
NY (what is this?)  (verify)

Mestanolone is the 17α-methylated version of dihydrotestosterone (DHT). The systematic name of mestanolone is: 17β-hydroxy-17α-methylandrost-3-one. It is an orally bioavailable androgenic steroid that is highly androgenic while only slightly anabolic. It is incapable of aromatization and is not an agonist of the progesterone receptor.

Dosage Information

Dosages range from 10 mg to 30 mg a day for males. Women should avoid Mestanolone for it is very androgenic. Long term use, more than 12 weeks should be avoided do to hepatoxicity. Since Mestanolone is unable to convert to estrogen, it is very useful during cutting phases or when one wishes to avoid excess weight gain.

Synonyms

Mestanolone is also known as methylandrostanolone or 17alpha-methylandrostanolone.