Aspartoacylase
From Infogalactic: the planetary knowledge core
aspartoacylase (Canavan disease) | |
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Identifiers | |
Symbol | ASPA |
Entrez | 443 |
HUGO | 756 |
OMIM | 608034 |
RefSeq | NM_000049 |
UniProt | P45381 |
Other data | |
EC number | 3.5.1.15 |
Locus | Chr. 17 p13-ter |
aspartoacylase (aminocyclase) 3 | |
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Identifiers | |
Symbol | ACY3 |
Entrez | 91703 |
HUGO | 24104 |
RefSeq | NM_080658 |
UniProt | Q96HD9 |
Other data | |
Locus | Chr. 11 q13 |
Aspartoacylase (EC 3.5.1.15, aminoacylase II, N-acetylaspartate amidohydrolase, acetyl-aspartic deaminase, acylase II) is a hydrolase enzyme with system name N-acyl-L-aspartate amidohydrolase.,[1][2] which breaks down N-acetylaspartate. A deficiency is associated with Canavan disease.This enzyme catalyses the following chemical reaction
- N-acyl-L-aspartate + H2O a carboxylate + L-aspartate
References
External links
- aspartoacylase at the US National Library of Medicine Medical Subject Headings (MeSH)
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