5-APDI

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Indanylaminopropane
Indanylaminopropane.svg
Systematic (IUPAC) name
(±)-1-(2,3-dihydro-1H-inden-5-yl)propan-2-amine
Clinical data
Legal status
  • UK: Class B
  • Uncontrolled (but may be covered under the Federal Analog Act in the US and under similar bills in other countries)
Routes of
administration		 Oral
Identifiers
CAS Number 13396-94-6 N
ATC code none
PubChem CID: 192600
ChemSpider 167142 YesY
ChEMBL CHEMBL6842 YesY
Synonyms 1-(5-indanyl)-2-aminopropane
Chemical data
Formula C12H17N
Molecular mass 175.27 g/mol
  • c1cc(cc2c1CCC2)CC(N)C
  • InChI=1S/C12H17N/c1-9(13)7-10-5-6-11-3-2-4-12(11)8-10/h5-6,8-9H,2-4,7,13H2,1H3 YesY
  • Key:QYVNZHBQYJRLEX-UHFFFAOYSA-N YesY
  (verify)

5-(2-Aminopropyl)-2,3-dihydro-1H-indene (5-APDI), also known as indanylaminopropane (IAP), IAP (psychedelic), 2-API(2-aminopropylindane), indanametamine, and, incorrectly, as indanylamphetamine,[1] is an entactogen and psychedelic drug of the amphetamine family.[2][3] It has been sold by online vendors through the Internet and has been encountered as a designer drug since 2003,[1] but its popularity and availability has diminished in recent years.

5-APDI acts as a potent and weakly selective serotonin releasing agent (SSRA) with IC50 values of 82 nM, 1,848 nM, and 849 nM for inhibiting the reuptake of serotonin, dopamine, and norepinephrine, respectively.[2][3] It fully substitutes for MBDB but not amphetamine in trained animals, though it does produce disruption for the latter at high doses.[2]

5-ADPI has been classified as a class B drug under the Misuse of Drugs Act 1971 since 10 June 2014.

See also

References

  1. ↑ 1.0 1.1 Lua error in package.lua at line 80: module 'strict' not found.
  2. ↑ 2.0 2.1 2.2 Lua error in package.lua at line 80: module 'strict' not found.
  3. ↑ 3.0 3.1 Lua error in package.lua at line 80: module 'strict' not found.

External links

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