Vesicle-associated membrane protein 8

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Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Vesicle-associated membrane protein 8 is a protein that in humans is encoded by the VAMP8 gene.[1][2][3]

Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. It is associated with the perinuclear vesicular structures of the early endocytic compartment. It has been found that VAMP8 interacts specifically with the soluble NSF-attachment protein (alpha-SNAP), most likely through an VAMP8-containing SNARE complex.[3]

Interactions

Vesicle-associated membrane protein 8 has been shown to interact with STX4,[4][5] SNAP23,[4][6] STX1A,[7] STX8[8] and STX7.[8][9]

References

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Further reading

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  1. ↑ Lua error in package.lua at line 80: module 'strict' not found.
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  3. ↑ 3.0 3.1 Lua error in package.lua at line 80: module 'strict' not found.
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  8. ↑ 8.0 8.1 Lua error in package.lua at line 80: module 'strict' not found.
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