Tribendimidine

Tribendimidine
	File:Tribendimidine.svg
Systematic (IUPAC) name
	N,N'-bis(4-(1-dimethylamino)ethylideneaminophenyl)-1,4; -phenylene dimethylidyneamine
Identifiers
CAS Number	115103-15-6
ATC code	none
PubChem	CID: 3086564
ChemSpider	2343161
ChEMBL	CHEMBL427256
Chemical data
Formula	C28H32N6
Molecular mass	452.594 g/mol
	SMILES N(=C/c2ccc(\C=N\c1ccc(/N=C(/N(C)C)C)cc1)cc2)\c3ccc(\N=C(\N(C)C)C)cc3 ;
	InChI InChI=1S/C28H32N6/c1-21(33(3)4)31-27-15-11-25(12-16-27)29-19-23-7-9-24(10-8-23)20-30-26-13-17-28(18-14-26)32-22(2)34(5)6/h7-20H,1-6H3/b29-19+,30-20+,31-21+,32-22+ ; Key:XOIOGKHKNQYULW-HTNNXBMUSA-N ;
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Tribendimidine is a broad-spectrum anthelmintic agent developed in China, at the National Institute of Parasitic Diseases in Shanghai. It is a derivative of amidantel.^[1]

In clinical trials, it was highly effective in treating ankylostomiasis, ascariasis and enterobiasis.^[2] However, animal studies suggest it is ineffective in treating Schistosoma mansoni or Fasciola hepatica disease.^[1]

References

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