TFE3
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Transcription factor E3 is a protein that in humans is encoded by the TFE3 gene.[1][2][3]
Function
TFE3, a member of the helix-loop-helix family of transcription factors, binds to the mu-E3 motif of the immunoglobulin heavy-chain enhancer and is expressed in many cell types (Henthorn et al., 1991).[supplied by OMIM][3]
Interactions
TFE3 has been shown to interact with:
- E2F3,[4]
- Microphthalmia-associated transcription factor,[5][6] and
- Mothers against decapentaplegic homolog 3[7][8]
Translocations
A proportion of renal carcinomas (RCC) that occur in young patients are associated with translocations involving the TFE3 gene at chromosome Xp11.2 PRCC
References
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<references />, or <references group="..." />Further reading
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This article on a gene on the human X chromosome and/or its associated protein is a stub. You can help Wikipedia by expanding it. |
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