SKP1A
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). S-phase kinase-associated protein 1 is an enzyme that in humans is encoded by the SKP1 gene.[1][2][3]
This gene encodes a protein that is a member of the SCF ubiquitin ligase protein complex. It binds to F-box proteins (proteins containing an F-box motif), such as cyclin F, S-phase kinase-associated protein 2, and other regulatory proteins involved in ubiquitin dependent proteolysis.[4] The encoded protein also collaborates with a network of proteins to control beta-catenin levels and affects the activity level of beta-catenin dependent TCF transcription factors. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.
Interactions
SKP1A has been shown to interact with:
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References
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<references />, or <references group="..." />Further reading
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