Reticular pigmented anomaly of the flexures
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| Reticular pigmented anomaly of the flexures | |
|---|---|
| Classification and external resources | |
| Specialty | Lua error in Module:Wikidata at line 446: attempt to index field 'wikibase' (a nil value). |
| OMIM | 179850 |
| Patient UK | Reticular pigmented anomaly of the flexures |
Reticular pigmented anomaly of the flexures (also known as "Dark dot disease," and "Dowling–Degos' disease") is a fibrous anomaly of the flexures or bending parts of the axillae, neck and inframammary/sternal areas.[1]:856 It is an autosomal-dominant pigmentary disorder that may appear in adolescence or adulthood. This condition is due to mutations in structural/desmosomal proteins found within stratified squamous epithelium.[2]
Dark dot disease is associated with KRT5.[3]
See also
References
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- ↑ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
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