Picornavirus internal ribosome entry site (IRES)

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Picornavirus internal ribosome entry site (IRES)
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Predicted secondary structure and sequence conservation of IRES_Picorna
Identifiers
Symbol IRES_Picorna
Rfam RF00229
Other data
RNA type Cis-reg; IRES
Domain(s) Viruses
GO 0043022
SO 0000243

This family represents the Picornavirus internal ribosome entry site (IRES). IRES elements allow cap and end-independent translation of mRNA in the host cell. It has been found that La autoantigen (La) is required for Coxsackievirus B3 (CVB3) IRES-mediated translation, and it has been suggested that La may be required for the efficient translation of the viral RNA in the pancreas.[1][2]

References

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External links

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