MCM5
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). DNA replication licensing factor MCM5 is a protein that in humans is encoded by the MCM5 gene.[1][2][3]
Function
The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.[3]
See also
Interactions
MCM5 has been shown to interact with:
- Cell division cycle 7-related protein kinase,[4]
- MCM2,[4][5]
- MCM3,[4][5]
- MCM7,[4][5][6]
- ORC2L,[4]
- ORC6L,[4] and
- STAT1.[5][7]
References
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Further reading
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