Holin superfamily V

The Holin superfamily V is a group of integral membrane transport proteins. There are seven different holin superfamilies in total. In general, these proteins are believed to play a role in regulated cell death, although functionality varies between families and individual members. The Holin superfamily V includes the TC families:

• 1.E.21 - The Listeria Phage A118 Holin (Hol118) Family
• 1.E.29 - The Holin Hol44 (Hol44) Family

Superfamily V includes protein families classified in the Transporter Classification Database as TC# 1.E.21 and TC# 1.E.29. Both families possess members from Firmicutes, Actinobacteria and Chloroflexi. Proteins of this superfamily all appear to have 3 transmembrane segments (TMSs) and have average sizes of 97 and 101 amino acyl residues (aas), respectively.

See also

• Holin
• Lysin
• Transporter Classification Database