EF5

For other uses, see EF-5.

EF5

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Names
IUPAC name 2-(2-Nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl)acetamide
Other names NSC-684681; EF-5
Identifiers
CAS Number	152721-37-4 Y
ChemSpider	344807 Y
Jmol 3D model	Interactive image
PubChem	389053
UNII	383HJ2T87O Y
InChI InChI=1S/C8H7F5N4O3/c9-7(10,8(11,12)13)4-15-5(18)3-16-2-1-14-6(16)17(19)20/h1-2H,3-4H2,(H,15,18) Y Key: JGGDSDPOPRWSCX-UHFFFAOYSA-N Y
SMILES O=[N+]([O-])c1nccn1CC(=O)NCC(F)(F)C(F)(F)F
Properties
Chemical formula	C8H7F5N4O3
Molar mass	302.16 g·mol−1
Vapor pressure	{{{value}}}
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Y verify (what is YN ?)
Infobox references

EF5 is a nitroimidazole used in oncology research. Due to its similarity in chemical structure to etanidazole, EF5 binds in cells displaying hypoxia.

The ¹⁸F-radiolabeled derivative of EF5 is being studied for its possibility to be used in positron emission tomography (PET) to detect low levels of oxygen in brain tumors. This can help show how a tumor will respond to treatment.