CHD4
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Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Chromodomain-helicase-DNA-binding protein 4 is an enzyme that in humans is encoded by the CHD4 gene.[1][2][3]
Function
The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein.[3]
Interactions
CHD4 has been shown to interact with HDAC1,[4][5][6] Histone deacetylase 2,[6][7][8] MTA2,[4] SATB1[9] and Ataxia telangiectasia and Rad3 related.[8]
References
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<references />, or <references group="..." />Further reading
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