Bateson–Dobzhansky–Muller model
The Bateson-Dobzhansky-Muller Model[1] is a model of the evolution of genetic incompatibility. The theory was first described by William Bateson in 1909,[2] then independently described by Theodosius Dobzhansky in 1934,[3] and later elaborated by Herman Muller.
The model attempts to explain how incompatibilities between closely related species develop without either of them going through an adaptive valley. In its simplest form the model shows that changes in at least two loci are required to cause hybrid incompatibility, or at least a decrease in fitness between individuals from two ancestrally identical, but allopatric populations. This is based on the idea that a new allele which has arisen at one locus in one population should not cause decreased fitness when placed into the identical (except for one allele) genetic background of the second population. Therefore another allele at a second locus which is incompatible with the first must have arisen.
See also
References
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