Acetone carboxylase

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acetone carboxylase
Identifiers
EC number 6.4.1.6
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, an acetone carboxylase (EC 6.4.1.6) is an enzyme that catalyzes the chemical reaction

acetone + CO2 + ATP + 2 H2O \rightleftharpoons acetoacetate + AMP + 2 phosphate

The 4 substrates of this enzyme are acetone, CO2, ATP, and H2O, whereas its 3 products are acetoacetate, AMP, and phosphate.

This enzyme belongs to the family of ligases, specifically those forming carbon-carbon bonds. The systematic name of this enzyme class is acetone:carbon-dioxide ligase (AMP-forming).

References

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