ASCL2
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Achaete-scute complex homolog 2 (Drosophila), also known as ASCL2, is an imprinted human gene.[1]
Function
This gene is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. Involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system.[1]
Interactions
ASCL2 has been shown to interact with NCOA6[2] and RBBP5.[2]
References
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<references />, or <references group="..." />Further reading
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