Platelet-rich fibrin
Platelet-rich fibrin (PRF) or leucocyte- and platelet-rich fibrin (L-PRF) is a second-generation PRP where autologous platelets and leucocytes are present in a complex fibrin matrix[1][2] to accelerate the healing of soft and hard tissue[3] and is used as a tissue-engineering scaffold for endodontics.[4]
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Dentistry
Socket preservation
Socket preservation, a procedure to reduce bone loss after tooth extraction to preserve the dental alveolus (tooth socket) in the alveolar bone. A platelet-rich fibrin (PRF) membrane containing bone growth enhancing elements can be stitched over the wound or a graft material or scaffold is placed in the socket of an extracted tooth at the time of extraction. The socket is then directly closed with stitches or covered with a non-resorbable or resorbable membrane and sutured.
Sinus lift
A platelet-rich fibrin can be used if a sinus lift is required for a dental implant.[5][6]
Guided bone and tissue regeneration
PRF is used in guided bone and tissue regeneration[7]
Regenerative endodontics
PRF enhances alveolar bone augmentation[8] and necrotic dental pulp and open tooth apex can be revitalized in regenerative endodontics with platelet-rich fibrin.[9]
See also
References
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