Glycine receptor, alpha 1
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Glycine receptor subunit alpha-1 is a protein that in humans is encoded by the GLRA1 gene.[1][2]
Function
The inhibitory glycine receptor mediates postsynaptic inhibition in the spinal cord and other regions of the central nervous system. It is a pentameric receptor composed of alpha and beta subunits. The GLRB gene encodes the beta subunit of the receptor.[3]
Clinical signficance
Mutations in the gene have been associated with hyperekplexia, a neurologic syndrome associated with an exaggerated startle reaction.[4][5]
See also
References
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<references />, or <references group="..." />Further reading
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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